The main purpose of this study is to examine the relationship between organizational factors and corporate entrepreneurship in Iranian SMEs. Organizational factors consist of management support, organizational values, organizational culture, formal control, work independency and empowerment, environmental monitoring, and organizational communication. 251 data gathered from 50 Iranian SMEs. The result of multiple regression analysis showed that all factors have significant and positive effects on corporate entrepreneurship. The highest impact referred to work independency and empowerment while the lowest impact referred to organizational culture.