Research on ideological and political practice based on innovation and entrepreneurship education courses in colleges and universities is conducted in this paper. The value of practical activities of entrepreneurship education lies in its contribution to the overall development of society and The degree of satisfaction of the needs of comprehensive human development. Therefore, only by establishing the social value of the individual value of the individual, the personal value of the society, and the self-value of the individual are intrinsically unified. The effectiveness of entrepreneurship education can be improved only by establishing the concept of entrepreneurship education with the inner unity of individual social value, individual value of society and individual self-value. Education is the pillar and foundation of national innovation system, and university education and postgraduate education are the bases for cultivating high-level innovative talents. This paper gives the novel ideas and the detailed discussions are presented.