Mesgaran exploration area is located in South Khorasan province, 26 km south of Sarbisheh city. The mineral potential of coppersmiths is copper mineralization. According to 75 surface samples taken, the analysis results are examined using the method of radial artificial neural network and error propagation. Also, after training to see the networks, the results can be used for other places. The strength of this study is that it does not require costly analyses to predict copper levels in other parts of the range, and simple analyses can estimate copper levels with an acceptable probability percentage and use the results to advance operations. In this area, the neural method was identified with higher accuracy.