Diversified literacy is a new requirement for students' literacy in today's information globalization and culturally diverse society. In college English teaching, based on the theory of multiple reading and writing, this paper designs an information-based system to guide the teaching of college English. According to the four steps of multiple reading and writing teaching method, students are trained in visual reading and writing, media reading and writing, digital reading and writing, and digital reading and writing. Multiple reading and writing skills such as critical reading and writing. Master multiple ways to build a multi-modal teaching model, and optimize the available multi-modal resources to the greatest extent, so as to stimulate the interest of non-English majors in English learning and cultivate their multiple reading and writing skills Ability and comprehensive application ability of English.