Aiming at the problems of low mining accuracy, slow running speed, and large memory footprint when mining complex and large-scale data sets in biological information networks, a multi-dimensional data mining algorithm for biological information networks based on association rule mapping is proposed. At the same time, it analyzes the current situation of English teaching in higher vocational colleges and the problems existing in cultural teaching, which leads to how to cultivate students' cultural communication awareness and improve students' cross-cultural communication ability in English teaching activities in higher vocational colleges. , The online and offline college English blended teaching mode of the network platform, and the online and offline college English blended teaching strategy of the network platform is proposed.