Objective: To evaluate the potential harm of heavy metals to human health in drinking water in Jingzhou City. Methods In 2021-2022, heavy metals in drinking water in Jingzhou City were detected, and the health risks caused by drinking water routes were preliminarily evaluated. Results The qualification rates of arsenic (As), cadmium (Cd), hexavalent chromium (Cr6+), lead (Pb) and mercury (Hg) in drinking water in Jingzhou City were 100.0%. The carcinogenic risks of As, Cd, Cr6+ and Pb were 3.6×10-5/a, 1.5×10-5/a, 4.8×10-5/a, and 8×10-8/a, respectively, and the cumulative carcinogenic risk was 9.8×10-5/a, and the carcinogenic risk order of different populations was > in children > adult malesadult females; The non-carcinogenic risk values of As, Cd, Cr6+, Pb and Hg were 8.0×10-2/a, 4.8×10-4/a, 1.9×10-2/a, 6.8×10-3/a, 8.0×10-2/a, and the hazard index was 1.1×10-1/a, respectively, and the non-carcinogenic risk order of different populations was > in children > adult malesAdult females. Conclusion The concentrations of As, Cd, Cr6+ and Pb in drinking water in Jingzhou City conform to GB 5749-2022 "Sanitary Standards for Drinking Water", and the cumulative carcinogenic risk is acceptable. The non-carcinogenic health risks of As, Cd, Cr6+, Pb, and Hg are within acceptable limits for the U.S. Environmental Protection Agency.