Due to the emission of harmful gas that pollute the atmosphere and rising cost of Ordinary Portland Cement (OPC), the use of waste material is considering as a replacement for cement. In this research, the use of agricultural waste on experimental investigation on the use of Bamboo Leaf Ash (BLA) as a partial replacement for cement. The content of percentage replacement of OPC with BLA from 0%. 5%, 10% and 15% by weight with 0.4 and 0.5 water-cement ratios. The compressive strengths were tested with a total of 72 (150 x 150 x 150) mm concrete cubes according to American Concrete Institute (ACI) provisions at 7 days, 14 days and 28 days respectively. In this study, local product of ‘Apache’ brand Portland cement, ‘wanet’ bamboo leaves, crushed stones and river sand were used. The chemical composition of BLA are tested by Energy Dispersive X-ray Fluorescence Spectroscopy (EDXRF) method. Research findings have carried out that the workability and strength of the concrete depend on the percentage of the ash, water-cement ratio, mixing time and age of the curing days. In this research, 5% and 10% BLA was optimum for medium grade concrete. As a conclusion, BLA have a high silica content and good supplementary cementitious properties and so it can be used for partial replacement of concrete for reducing environmental wastes and emission of carbon dioxide (CO2) in production of cement and reducing costs.