Power Distribution system consists of tie and sectionalizing switches. Tie switches are normally open and sectionalizing switches are normally close. Reconfiguration can be used for the objectives of loss reduction, load balancing, etc. The change in network configuration is performed by opening sectionalizing (normally closed) and closing tie (normally open) switches of the network. Inputs data are based on real time data collected from 66/11kV substations under Yangon Electricity Supply Board (YESB). The proposed method is tested on 90-Bus, overhead AC radial distribution network of North Dagon Township (BaeLi substation), Yangon, Myanmar. The distribution network for existing and reconfiguration conditions are simulated by MATLAB software. This paper is focusing on evaluating the power loss reduction.