Three different varieties of muskmelons (Cucumis melo) bought from local market in the city of Toungoo, Pegu Region, Myanmar, were analyzed in this research. pH of these muskmelon ranged from 6.35 to 6.89 and found to be comparable. Highest protein content of 10.66% was observed in white-fleshed, non-netted, smooth surface melon, Muskmelon samples contained low fiber contents of 2.35% to 5.00% and thus, it was not a good source of fiber. Highest available carbohydrate content of 55.61% was observed in green-fleshed netted melon. By AAS analysis potassium was found to be the highest (5016-5037mg/100g) followed by sodium (1249-1487/100g), calcium (312.0-715.1mg/100g), manganese (11.3-15.7mg/100g), copper (5.9-11.6mg/100g) and zinc (2.6-5.1mg/100). Iodometric titrimetric analysis revealed that total sugar contents were in range of 9.00-9.72%. Lowest reducing sugar (1.50%) was found in white-fleshed, non-netted melon. Lowest reducing sugar as a percentage of total sugar of 15.43% was also observed in white-fleshed variety.